Lab Test : Lactic Acid, Cerebrospinal Fluid

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Alternate:CSF Lactic Acid; CSF Lactate
Includes:Lactic acid
Department:Chemistry
Phone:(937) 641-3428
SQ Code:CLA
Available:Daily, 24 hours
Turnaround:30 minutes
Specimen:Cerebrospinal fluid
Volume:0.5 mL spinal fluid
Container:Sterile spinal fluid collection tube
Temperature:Specimen must be PLACED ON ICE and delivered to lab within 30 minutes after collection.
Rejection:In transport longer than 30 minutes, bloody tap, specimen not on ice.
Normal:0.6-2.2 mmol/L. Lactate in CSF normally parallels blood levels. With biochemical alterations in the CNS, CSF lactate values change independently of blood values.
Uses:Increased CSF levels are noted in cerebrovascular accidents, intracranial hemorrhage, bacterial meningitis, epilepsy, and other CNS disorders. Aseptic/viral meningitis lactate levels are usually not elevated and therefore used to discriminate between viral and bacterial meningitis, but the clinical utility has been questioned.
Limitations:The effects of hemolysis and xanthochromia in CSF have not been evaluated.
Method:Enzymatic two filter endpoint (NAD/NADH)
 

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