Lab Test : Methylenetetrahdrofolate reductase C677T/A1298C gene mutations

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Alternate:MTHFR, C677T, A1298C, MTHFR thermolabile variant
Department:Molecular Genetics Lab
Phone:(937) 641-3262
Available:Lab open M-F 7:30a-4:00p. Specimens accepted daily, 24 hrs. Specimens batched and test run weekly.
Turnaround:7 days
Volume:0.5 ml
Temperature:Room temperature for not more than 24 hrs. Can be stored at 4 degrees C for 1 wk.
Rejection:Will attempt to extract DNA and perform assay if hemolysis or clotting are present or if blood is in a preservative other than EDTA.
Normal:N/N genotype for each locus
Uses:To detect the methylenetetrahydrofolate reductase mutation associated with hyperhomocysteinemia and vascular disease. This test is also included in the Thrombophilia Panel.
Limitations:This asssay detects ONLY the C677T and A1298C mutations in the MTHFR gene.
Method:FDA-Approved GenMark eSensor XT-8

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