|Alternate:||Angelman DNA; Prader-Willi DNA|
|Department:||Molecular Genetics Lab|
|Available:||Lab open Mon - Fri 7:30 AM - 4:00 PM. Specimens accepted daily, 24 hours. Specimens batched and test run every 2 weeks as needed.|
|Temperature:||Room temperature for not more than 24 hours. Can be stored at 4 degrees C for 1 week.|
|Rejection:||Will attempt to extract DNA and perform assay if hemolysis or clotting are present or if blood is in a preservative other than EDTA.|
|Uses:||To detect deletion or uniparental inheritance of 15q11-q13 associated with Angelman and Prader-Willi syndromes.|
|Limitations:||This assay detects ONLY the deletion or unipatental inheritance of the 15q11-q13 region.|
|Method:||Methylation-specific polymerase chain reaction (MS-PCR)|
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