Lab Test : Theophylline, Blood: Random, Peak, or Trough

Print this page Bookmark and Share
Alternate:Aminophylline
Includes:Random, Peak, or Trough Theophylline
Department:Chemistry
Phone:(937) 641-3428
SQ Code:THEO (RANDOM), THEP (PEAK), THET (TROUGH)
Available:Daily, 24 hours
Turnaround:Routine: 3 hours, STAT: 30 minutes
Specimen:Blood
Volume:0.2 mL
Container:3 mL green top tube or green microtainer (sodium heparin)
Temperature:Deliver to lab within 30 minutes.
Rejection:N/A
Normal:10-20 µgrams/mL
Toxic: greater than 20 µgrams/mL
Critical: greater than 20 µgrams/mL
Uses:Monitor therapeutic drug level; Evaluate theophylline toxicity Time to collect: Trough: 30 minutes prior to next dose. Peak: One hour after oral dose; 30 minutes after IV infusion
Limitations:A theophylline metabolite, 1,3-dimethyluric acid may cause falsely elevated results in uremic patients. A minor metabolite is caffeine. In the premature neonate, approximately 50% of theophylline is excreted unchanged in the urine and the remaining 50% undergoes metabolism to caffeine and 1,3-dimethyluric acid.
Method:PETINIA (Particle enhanced turbidimetric inhibition immunoassay)
 

Sign up for Pediatric Link

Finding the latest trusted child health and safety information doesn't have to be hard. Pediatric Link, Dayton Children's e-newsletter offers timely and up-to-date information for health care professionals from the experts you trust at Dayton Children's.  Sign up

Upcoming Events

Car Seat Safety Check at Russell's Point Municipal Building

Play golf at the world-class NCR Country Club golf course to benefit Dayton Children’s Pediatric Cancer Care Center. Enjoy the Hoopla festivities featuring dinner and an outstanding silent auction and a guest presentations from our brave Dayton Children's ambassador fighting cancer.

Car Seat Safety Check

View full event calendarView full event calendar

The Right Experts

Just right for all kids

Accreditations

The Children's Medical Center of Dayton Dayton Children's
The Right Care for the Right Reasons

One Children's Plaza - Dayton, Ohio - 45404-1815
937-641-3000
www.childrensdayton.org