Lab Test : Insulin-like growth factor (IGF-1)

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Alternate:IGF1; Somatomedin C
Includes:IGF1
Department:Chemistry
Phone:(937) 641-3908
SQ Code:CIGF1
Available:Mon - Fri, first shift only
Turnaround:48 hours
Specimen:blood
Volume:0.7 mL
Container:4 mL red top tube
Temperature:Samples should be transported to the laboratory within 20 minutes.
Rejection:Gross hemolysis or gross lipemia. No EDTA or Heparinized samples.
Normal:Males
2 months:17-248 ng/mL
6 years: 88-474 ng/mL
9 years:110-565 ng/mL
12 years: 202-957 ng/mL
16 years: 182-780 ng/mL
Females
2 months: 17-248 ng/mL
6 years: 88-474 ng/mL
9 years: 117-771 ng/mL
12 years: 261-1096 ng/mL
16 years:182-780 ng/mL.
Uses:In children with unequivocal growth hormone deficiency(GHD) and severe hypothyroidism, IGF-1 values are consistently low. Furthermore , the finding of normal IGF-1 values makes the diagnosis of growth hormone deficiency less likely. Low IGF-1 values are not in themselves diagnostic of GHD and should be followed up by additional studies of GH secretion. In cases of hypoprolactinemia or craniopharyngioma, IGF-1 values may be normal in patients with growth hormone deficiency. Low IGF-1 results can be found in apparently normal children below 5 years of age. Hypopituitary children can exhibit levels of IGF-1 into the low normal range for their age. For such individuals, further tests including growth hormone perturbation studies may be needed.
Limitations:N/A
Method:Sandwich chemiluminescence immunoassay
 

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