|Department:||Biochemical Genetics Lab|
|Available:||Lab open M-F 7:30a-4:00p. Specimens accepted daily, 24 hrs. Specimens batched and test run as needed.|
|Turnaround:||Routine 4 days; STAT 24 hours|
|Container:||Sodium heparin preferred, lithium heparin accepted|
|Temperature:||Give specimen to send-out tech (1st shift) or core lab tech (2nd/3rd shift, weekends, holidays). Spin, remove and freeze plasma at -20 degrees C. Specimen should not be left at room temperature for more than 2 hours.|
|Rejection:||Specimens should be as fresh as possible and processed immediately. All samples will be run. Sub-optimal handling is noted in report.|
|Normal:||0 - 1 month 55 - 147 umol/L; 1 month - 2 months 22 - 108 umol/L; 2 months - 18 years 24 - 115 umol/L; 18 years + 34 - 112 umol/L|
|Uses:||To monitor tyrosine levels in patients with PKU.|
|Limitations:||Protein intake may affect tyrosine levels.|
|Method:||ion exchange chromatography|
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